Saccharin was a artificial sugar than it was getting to much heat so the corporations made a rebranding to aspartame. Sucralose is aspartame read on the web these are all the same thing but different branding.
If your body can't accept anything natural why would anything artificial and synthetic be any better? Just doesn't make sense ...
Try again.... Please do some actual research, not just use bro-science.
These are all *very* different chemical compounds, not just re-branding of the same thing.
Sucralose
http://en.wikipedia.org/wiki/Sucralose (Splenda)
Saccharin
http://en.wikipedia.org/wiki/SaccharinAspartame
http://en.wikipedia.org/wiki/Aspartame (Equal, NutraSweet, and Canderel)
Each is branded by different companies, and goes by a number of names....
(If lists are helpful, I'm happy to provide a few for each.)
So far as why some can tolerate artificial ones better than natural...
it has to do with Glucose Intolerance....
Biochemically, none of the three above sweeteners break down to raise one's blood glucose.
Table Sugar (Sucrose) does...